{"id":6105,"date":"2014-03-28T14:50:15","date_gmt":"2014-03-28T18:50:15","guid":{"rendered":"http:\/\/www.ac3m.org\/?p=6105"},"modified":"2014-03-28T14:53:28","modified_gmt":"2014-03-28T18:53:28","slug":"un-plan-de-navigation-des-genes-humains","status":"publish","type":"post","link":"https:\/\/www.ac3m.org\/?p=6105","title":{"rendered":"Un \u00ab\u00a0plan de navigation\u00a0\u00bb des g\u00e8nes humains"},"content":{"rendered":"<p><strong><span style=\"color: #800000;\">Dans la revue <em>Nature<\/em>, une \u00e9quipe de 250 chercheurs issus de 20 pays, au sein de l&rsquo;Institut japonais Riken, vient de publier la premi\u00e8re carte montrant la mani\u00e8re dont les g\u00e8nes humains sont r\u00e9gul\u00e9s dans les diff\u00e9rents types de cellules.\u00a0<\/span><\/strong><\/p>\n<div id=\"attachment_6106\" style=\"width: 110px\" class=\"wp-caption alignleft\"><a href=\"https:\/\/www.ac3m.org\/wp-content\/uploads\/2014\/03\/g\u00e8nes.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-6106\" class=\"size-full wp-image-6106\" alt=\"Photo g\u00e8n\u00e9thique\" src=\"https:\/\/www.ac3m.org\/wp-content\/uploads\/2014\/03\/g\u00e8nes.jpg\" width=\"100\" height=\"75\" \/><\/a><p id=\"caption-attachment-6106\" class=\"wp-caption-text\">Photo g\u00e8n\u00e9thique<\/p><\/div>\n<p>Par ce projet, intitul\u00e9 FANTOM5, les chercheurs ont montr\u00e9 \u00ab\u00a0<em>comment un r\u00e9seau de commutateurs, construit dans l&rsquo;ADN humain, contr\u00f4le o\u00f9 et quand les g\u00e8nes sont activ\u00e9s et d\u00e9sactiv\u00e9s<\/em>\u00ab\u00a0.<\/p>\n<p>Alistair Forrest, scientifique coordinateur de FANTOM5 explique: \u00ab\u00a0<em>les humains sont des organismes multicellulaires compos\u00e9s d&rsquo;au moins 400 types de cellules diff\u00e9rents. Cette belle diversit\u00e9 de types de cellules nous permet de voir, penser, entendre, bouger, de combattre les infections &#8211; tout cela est cod\u00e9 dans le m\u00eame g\u00e9nome<\/em>\u00ab\u00a0. Il poursuit en expliquant que la diff\u00e9rence entre les cellules varie en fonction de la partie du g\u00e9nome que celles-ci utilisent. Ainsi, \u00e0 titre d&rsquo;exemple, les g\u00e8nes utilis\u00e9s par les cellules du cerveau et du foie ne sont pas les m\u00eames. Les deux types de cellules ne travaillent donc pas de la m\u00eame mani\u00e8re.<\/p>\n<p>Par cons\u00e9quent, ce travail pourrait aider les chercheurs \u00e0 mieux cibler les g\u00e8nes li\u00e9s \u00e0 certaines maladies.\u00a0Reuters.com (Kate Kelland) 26\/03\/2014<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dans la revue Nature, une \u00e9quipe de 250 chercheurs issus de 20 pays, au sein de l&rsquo;Institut japonais Riken, vient de publier la premi\u00e8re carte montrant la mani\u00e8re dont les g\u00e8nes humains sont r\u00e9gul\u00e9s dans les diff\u00e9rents types de cellules.\u00a0 Par ce projet, intitul\u00e9 FANTOM5, les chercheurs ont montr\u00e9 \u00ab\u00a0comment un r\u00e9seau de commutateurs, construit [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,14],"tags":[733,731,732],"class_list":["post-6105","post","type-post","status-publish","format-standard","hentry","category-actualites","category-societe","tag-cellules","tag-genes-humains","tag-navigation"],"_links":{"self":[{"href":"https:\/\/www.ac3m.org\/index.php?rest_route=\/wp\/v2\/posts\/6105","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ac3m.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ac3m.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ac3m.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ac3m.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6105"}],"version-history":[{"count":1,"href":"https:\/\/www.ac3m.org\/index.php?rest_route=\/wp\/v2\/posts\/6105\/revisions"}],"predecessor-version":[{"id":6107,"href":"https:\/\/www.ac3m.org\/index.php?rest_route=\/wp\/v2\/posts\/6105\/revisions\/6107"}],"wp:attachment":[{"href":"https:\/\/www.ac3m.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6105"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ac3m.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6105"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ac3m.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6105"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}